Why our hair turns gray? Human degeneration will always be medical concern, and every research is meaningful. Senile graying of human hair has been the subject of intense research since ancient times.
New research shows that hair turns gray as a result of a chemical chain reaction that causes hair to bleach itself from the inside out.
The process starts when there is a dip in levels of an enzyme called catalase. That catalase shortfall means that the hydrogen peroxide that naturally occurs in hair can't be broken down.
Research demonstrate almost absent catalase and methionine sulfoxide reductase A and B protein expression via immunofluorescence and Western blot in association with a functional loss of methionine sulfoxide repair in the entire gray hair follicle. Here can be concluded that H2O2-mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair
As the research summary, concept of H2O2-induced oxidative damage in the entire human hair follicle, inclusive of the hair shaft, as a key element in senile hair graying, which does not exclusively affect follicle melanocytes. This new insight could open new strategies for intervention and reversal of the hair graying process.
J. M. Wood, H. Decker, H. Hartmann, B. Chavan, H. Rokos, J. D. Spencer, S. Hasse, M. J. Thornton, M. Shalbaf, R. Paus, and K. U. Schallreuter
Wood, J. The FASEB Journal, Feb. 23, 2009; online edition.
News release, Federation of American Societies for Experimental Biology.
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